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The dimerization/packaging sequence is dispensable for both the formation of high-molecular-weight RNA complexes within retroviral particles and the synthesis of proviruses of normal structure.

Retroviral particles contain a dimer of two genomic RNA molecules, linked by noncovalent intermolecular bonds. Studies by electron microscopy of viral RNA extracted from virions as well as in vitro studies have implicated a sequence, designated the dimer linkage sequence (DLS), in the dimerization p...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Tchénio, T, Heidmann, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7815486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.2.1079-1084.1995
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