Co-Targeting the PI3K and RAS Pathways for the Treatment of Neuroendocrine Tumors

BACKGROUND: The precise involvement of the PI3K/mTOR and RAS/MEK pathways in carcinoid tumors is not well defined. Therefore, the purpose of our study was to evaluate the role these pathways play in carcinoid cell proliferation, apoptosis, and secretion and to determine the effects of combined treat...

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Detalhes bibliográficos
Main Authors: Valentino, Joseph D., Li, Jing, Zaytseva, Yekaterina Y., Mustain, W. Conan, Elliott, Victoria A., Kim, Ji Tae, Harris, Jennifer W., Campbell, Katherine, Weiss, Heidi, Wang, Chi, Song, Jun, Anthony, Lowell, Townsend, Courtney M., Evers, B. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947505/
https://ncbi.nlm.nih.gov/pubmed/24443523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1897
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