Co-Targeting the PI3K and RAS Pathways for the Treatment of Neuroendocrine Tumors

BACKGROUND: The precise involvement of the PI3K/mTOR and RAS/MEK pathways in carcinoid tumors is not well defined. Therefore, the purpose of our study was to evaluate the role these pathways play in carcinoid cell proliferation, apoptosis, and secretion and to determine the effects of combined treat...

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Detaylı Bibliyografya
Asıl Yazarlar: Valentino, Joseph D., Li, Jing, Zaytseva, Yekaterina Y., Mustain, W. Conan, Elliott, Victoria A., Kim, Ji Tae, Harris, Jennifer W., Campbell, Katherine, Weiss, Heidi, Wang, Chi, Song, Jun, Anthony, Lowell, Townsend, Courtney M., Evers, B. Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947505/
https://ncbi.nlm.nih.gov/pubmed/24443523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1897
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