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Microarray Analysis Identifies Changes in Inflammatory Gene Expression in Response to Amyloid-β Stimulation of Cultured Human Retinal Pigment Epithelial Cells

PURPOSE: Age-related macular degeneration (AMD) is a common cause of irreversible vision loss in the elderly. The hypothesis was that in vitro stimulation of RPE cells with Aβ(1-40), a constituent of drusen, promotes changes in gene expression and cellular pathways associated with the pathogenesis o...

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Autors principals: Kurji, Khaliq H., Cui, Jing Z., Lin, Tony, Harriman, David, Prasad, Shiv S., Kojic, Ljuba, Matsubara, Joanne A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947389/
https://ncbi.nlm.nih.gov/pubmed/19797223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3622
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