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Transcription-generated torsional stress destabilizes nucleosomes

As RNA Polymerase II (Pol II) transcribes a gene, it encounters an array of well-ordered nucleosomes. How it traverses through this array in vivo remains unresolved. One model proposes that torsional stress generated during transcription destabilizes nucleosomes ahead of Pol II. Here, we describe a...

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Bibliografiska uppgifter
Huvudupphovsmän: Teves, Sheila S., Henikoff, Steven
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947361/
https://ncbi.nlm.nih.gov/pubmed/24317489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2723
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