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Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors

PURPOSE: Here, we describe a novel interplay between NAD synthesis and degradation involved in pancreatic tumor growth. EXPERIMENTAL DESIGN: We used human pancreatic cancer cells both in vitro (cell culture experiments) and in vivo (xenograft experiments) to demonstrate the role of NAD synthesis and...

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Bibliografische gegevens
Hoofdauteurs: Chini, Claudia C.S., Gonzalez Guerrico, Anatilde M., Nin, Veronica, Camacho-Pereira, Juliana, Escande, Carlos, Barbosa, Maria Thereza, Chini, Eduardo N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947324/
https://ncbi.nlm.nih.gov/pubmed/24025713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0150
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