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Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors
PURPOSE: Here, we describe a novel interplay between NAD synthesis and degradation involved in pancreatic tumor growth. EXPERIMENTAL DESIGN: We used human pancreatic cancer cells both in vitro (cell culture experiments) and in vivo (xenograft experiments) to demonstrate the role of NAD synthesis and...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947324/ https://ncbi.nlm.nih.gov/pubmed/24025713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0150 |
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