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The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, is Crucial for Vascular Development

ENOX1 is a highly conserved NADH oxidase that helps to regulate intracellular nicotinamide adenine dinucleotide levels in many cell types including endothelial cells. Pharmacological and RNAi-mediated suppression of ENOX1 impairs surrogate markers of tumor angiogenesis/vasculogenesis, providing supp...

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Detalhes bibliográficos
Main Authors: Venkateswaran, Amudhan, Sekhar, Konjeti R., Levic, Daniel S., Melville, David B., Clark, Travis A, Rybski, Witold M., Walsh, Alexandra J., Skala, Melissa C., Crooks, Peter A., Knapik, Ela W., Freeman, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947320/
https://ncbi.nlm.nih.gov/pubmed/24247717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1981
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