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Nucleic Acid Oxidation: An early feature of Alzheimer’s disease

Studies of oxidative damage during the progression of Alzheimer’s disease (AD) suggest its central role in disease pathogenesis. To investigate levels of nucleic acid oxidation in both early and late stages of AD, levels of multiple base adducts were quantified in nuclear and mitochondrial DNA from...

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Detalhes bibliográficos
Main Authors: Bradley-Whitman, M. A., Timmons, M. D., Beckett, T. L., Murphy, M. P., Lynn, B. C., Lovell, M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947319/
https://ncbi.nlm.nih.gov/pubmed/24032632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12444
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