Oxidative modification of lipoic acid by HNE in Alzheimer disease brain()

Alzheimer disease (AD) is an age-related neurodegenerative disease characterized by the presence of three pathological hallmarks: synapse loss, extracellular senile plaques (SP) and intracellular neurofibrillary tangles (NFTs). The major component of SP is amyloid β-peptide (Aβ), which has been show...

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Detalhes bibliográficos
Main Authors: Hardas, Sarita S., Sultana, Rukhsana, Clark, Amy M., Beckett, Tina L., Szweda, Luke I., Murphy, M. Paul, Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757677/
https://ncbi.nlm.nih.gov/pubmed/24024140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.01.002
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