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Large-scale mass spectrometric detection of variant peptides resulting from non-synonymous nucleotide differences

Each individual carries thousands of non-synonymous single nucleotide variants (nsSNVs) in their genome, each corresponding to a single amino acid polymorphism (SAP) in the encoded proteins. It is important to be able to directly detect and quantify these variations at the protein level in order to...

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Autori principali: Sheynkman, Gloria M., Shortreed, Michael R., Frey, Brian L., Scalf, Mark, Smith, Lloyd M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947302/
https://ncbi.nlm.nih.gov/pubmed/24175627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr4009207
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