Semaphorin 7A is expressed on airway eosinophils and upregulated by IL-5 family cytokines

Semaphorin 7A (Sema7A) plays a major role in TGF-β1-induced lung fibrosis. Based on the accumulating evidence that eosinophils contribute to fibrosis/remodeling in the airway, we hypothesized that airway eosinophils may be a significant source of sema7A. In vivo, sema7A was expressed on the surface...

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Main Authors: Esnault, Stephane, Kelly, Elizabeth A., Johansson, Mats W., Liu, Lin Ying, Han, Shih-Tsung, Akhtar, Moneeb, Sandbo, Nathan, Mosher, Deane F., Denlinger, Loren C., Mathur, Sameer K., Malter, James S., Jarjour, Nizar N.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947215/
https://ncbi.nlm.nih.gov/pubmed/24333536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2013.11.009
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