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A site-specific genetic modification for induction of pluripotency and subsequent isolation of derived lung alveolar epithelial type II cells
Human induced pluripotent stem cells (hiPSCs) have great therapeutic potential in repairing defective lung alveoli. However, genetic abnormalities caused by vector-integrations and low efficiency in generating hiPSCs, as well as difficulty in obtaining transplantable hiPSC-derived cell types, are st...
Gorde:
Egile Nagusiak: | , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
2014
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947140/ https://ncbi.nlm.nih.gov/pubmed/24123810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1570 |
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