Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2.

MAP kinase-activated protein (MAPKAP) kinase-2 is activated in vivo by reactivating kinase (RK), a MAP kinase (MAPK) homologue stimulated by cytokines and cellular stresses. Here we show that in vitro RK phosphorylates human GST-MAPKAP kinase-2 at Thr25 in the proline-rich N-terminal region Thr222 a...

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Publicado en:	EMBO J
Autores principales:	Ben-Levy, R, Leighton, I A, Doza, Y N, Attwood, P, Morrice, N, Marshall, C J, Cohen, P
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8846784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00280.x
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