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Phase I Design for Completely or Partially Ordered Treatment Schedules
The majority of methods for the design of Phase I trials in oncology are based upon a single course of therapy, yet in actual practice it may be the case that there is more than one treatment schedule for any given dose. Therefore, the probability of observing a dose-limiting toxicity (DLT) may depe...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947103/ https://ncbi.nlm.nih.gov/pubmed/24114957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5998 |
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