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Prostate cancer derived prostatic acid phosphatase promotes an osteoblastic response in the bone microenvironment
Approximately 90 % of patients who die of prostate cancer (PCa) have bone metastases, often promoting osteoblastic lesions. We observed that 88 % of castration-resistant PCa (CRPC) bone metastases express prostatic acid phosphatase (PAP), a soluble secreted protein expressed by prostate epithelial c...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946934/ https://ncbi.nlm.nih.gov/pubmed/24242705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-013-9625-2 |
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