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Integrating Virtual and Biochemical Screening for Protein Tyrosine Phosphatase Inhibitor Discovery
Protein tyrosine phosphatases (PTPs) represent an important class of enzymes that mediate signal transduction and control diverse aspects of cell behavior. The importance of their activity is exemplified by their significant contribution to disease etiology with over half of all human PTP genes impl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946838/ https://ncbi.nlm.nih.gov/pubmed/23969317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.08.013 |
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