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Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate

Few preclinical models accurately depict normal human prostate tissue or primary prostate cancer (PCa). In vitro systems typically lack complex cellular interactions among structured prostatic epithelia and a stromal microenvironment, and genetic and molecular fidelity are concerns in both in vitro...

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Autori principali: Maund, Sophia L., Nolley, Rosalie, Peehl, Donna M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946793/
https://ncbi.nlm.nih.gov/pubmed/24296879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2013.141
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