Gender-Specific Potential Inhibitory Role of Ca2(+)/Calmodulin Dependent Protein Kinase Phosphatase (CaMKP) in Pressure-Overloaded Mouse Heart

BACKGROUND: Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) has been proposed as a potent regulator of multifunctional Ca(2+)/calmodulin-dependent protein kinases (i.e., CaMKII). The CaMKII-dependent activation of myocyte enhancer factor 2 (MEF2) disrupts interactions between MEF2-his...

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Autori principali: Prévilon, Miresta, Pezet, Mylène, Vinet, Laurent, Mercadier, Jean-Jacques, Rouet-Benzineb, Patricia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946626/
https://ncbi.nlm.nih.gov/pubmed/24608696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090822
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