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Bistability in the Ca(2+)/calmodulin-dependent protein kinase-phosphatase system.
A mathematical model is presented of autophosphorylation of Ca(2+)/calmodulin-dependent protein kinase (CaMKII) and its dephosphorylation by a phosphatase. If the total concentration of CaMKII subunits is significantly higher than the phosphatase Michaelis constant, two stable steady states of the C...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1301111/ https://ncbi.nlm.nih.gov/pubmed/11053103 |
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