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Negative regulation of multifunctional Ca(2+)/calmodulin-dependent protein kinases: physiological and pharmacological significance of protein phosphatases

Multifunctional Ca(2+)/calmodulin-dependent protein kinases (CaMKs) play pivotal roles in intracellular Ca(2+) signaling pathways. There is growing evidence that CaMKs are involved in the pathogenic mechanisms underlying various human diseases. In this review, we begin by briefly summarizing our kno...

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Detalhes bibliográficos
Main Authors: Ishida, A, Sueyoshi, N, Shigeri, Y, Kameshita, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2439855/
https://ncbi.nlm.nih.gov/pubmed/18454172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.127
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