Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy

Mutations in the connexin 26 gene (GJB2) are the most common genetic cause of deafness, leading to congenital bilateral non-syndromic sensorineural hearing loss. Here we report the generation of a mouse model for a connexin 26 (C×26) mutation, in which cre-Sox10 drives excision of the C×26 gene from...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Takada, Yohei, Beyer, Lisa A., Swiderski, Donald L., O’Neal, Aubrey L., Prieskorn, Diane M., Shivatzki, Shaked, Avraham, Karen B., Raphael, Yehoash
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946535/
https://ncbi.nlm.nih.gov/pubmed/24333301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2013.11.009
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares