Mice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organs

Connexins are components of gap junctions which facilitate transfer of small molecules between cells. One member of the connexin family, Connexin 26 (Cx26), is prevalent in gap junctions in sensory epithelia of the inner ear. Mutations of GJB2, the gene encoding Cx26, cause significant hearing loss...

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Bibliographic Details
Published in:Hear Res
Main Authors: Lee, Min Young, Takada, Tomoko, Takada, Yohei, Kappy, Michelle D., Beyer, Lisa A., Swiderski, Donald L., Godin, Ashley L., Brewer, Shannon, King, W. Michael, Raphael, Yehoash
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581988/
https://ncbi.nlm.nih.gov/pubmed/26232528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2015.07.018
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