Negatively Charged Metal Oxide Nanoparticles Interact with the 20S Proteasome and Differentially Modulate Its Biologic Functional Effects

The multicatalytic ubiquitin-proteasome system (UPS) carries out proteolysis in a highly orchestrated way and regulates a large number of cellular processes. Deregulation of the UPS in many disorders has been documented. In some cases, e.g. carcinogenesis, elevated proteasome activity has been impli...

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Main Authors: Falaschetti, Christine A., Paunesku, Tatjana, Kurepa, Jasmina, Nanavati, Dhaval, Chou, Stanley S., De, Mrinmoy, Song, MinHa, Jang, Jung-tak, Wu, Aiguo, Dravid, Vinayak P., Cheon, Jinwoo, Smalle, Jan, Woloschak, Gayle E.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946455/
https://ncbi.nlm.nih.gov/pubmed/23930940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn402416h
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