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Metastasis suppressor KISS1 appears to reverse the Warburg effect by enhancing mitochondrial biogenesis

Cancer cells tend to utilize aerobic glycolysis even under normoxic conditions, commonly called the “Warburg Effect.” Aerobic glycolysis often directly correlates with malignancy, but its purpose, if any, in metastasis remains unclear. When wild-type KISS1 metastasis suppressor is expressed, aerobic...

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Main Authors: Liu, Wen, Beck, Benjamin H., Vaidya, Kedar S., Nash, Kevin T., Feeley, Kyle P., Ballinger, Scott W., Pounds, Keke M., Denning, Warren L., Diers, Anne R., Landar, Aimee, Dhar, Animesh, Iwakuma, Tomoo, Welch, Danny R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946400/
https://ncbi.nlm.nih.gov/pubmed/24351292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1183
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