ChIP-Seq and RNA-Seq Reveal an AmrZ-Mediated Mechanism for Cyclic di-GMP Synthesis and Biofilm Development by Pseudomonas aeruginosa

The transcription factor AmrZ regulates genes important for P. aeruginosa virulence, including type IV pili, extracellular polysaccharides, and the flagellum; however, the global effect of AmrZ on gene expression remains unknown, and therefore, AmrZ may directly regulate many additional genes that a...

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Detalhes bibliográficos
Main Authors: Jones, Christopher J., Newsom, David, Kelly, Benjamin, Irie, Yasuhiko, Jennings, Laura K., Xu, Binjie, Limoli, Dominique H., Harrison, Joe J., Parsek, Matthew R., White, Peter, Wozniak, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946381/
https://ncbi.nlm.nih.gov/pubmed/24603766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003984
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