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Genetic and functional analyses of ZIC3 variants in congenital heart disease
Mutations in zinc-finger in cerebellum 3 (ZIC3) result in heterotaxy or isolated congenital heart disease (CHD). The majority of reported mutations cluster in zinc-finger domains. We previously demonstrated that many of these lead to aberrant ZIC3 subcellular trafficking. A relative paucity of N- an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946352/ https://ncbi.nlm.nih.gov/pubmed/24123890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22457 |
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