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Identification and Functional Analysis of ZIC3 Mutations in Heterotaxy and Related Congenital Heart Defects

Mutations in the zinc finger transcription factor ZIC3 cause X-linked heterotaxy and have also been identified in patients with isolated congenital heart disease (CHD). To determine the relative contribution of ZIC3 mutations to both heterotaxy and isolated CHD, we screened the coding region of ZIC3...

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Détails bibliographiques
Auteurs principaux: Ware, Stephanie M., Peng, Jianlan, Zhu, Lirong, Fernbach, Susan, Colicos, Suzanne, Casey, Brett, Towbin, Jeffrey, Belmont, John W.
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181916/
https://ncbi.nlm.nih.gov/pubmed/14681828
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