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Crystal Structures of the Novel Cytosolic 5′-Nucleotidase IIIB Explain Its Preference for m(7)GMP

5′-nucleotidases catalyze the hydrolytic dephosphorylation of nucleoside monophosphates. As catabolic enzymes they contribute significantly to the regulation of cellular nucleotide levels; misregulation of nucleotide metabolism and nucleotidase deficiencies are associated with a number of diseases....

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Detalhes bibliográficos
Main Authors: Monecke, Thomas, Buschmann, Juliane, Neumann, Piotr, Wahle, Elmar, Ficner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946280/
https://ncbi.nlm.nih.gov/pubmed/24603684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090915
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