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Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder
BACKGROUND: The 39,X(Y*)O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurobiology underlying these phenotypes is unclear, a...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946266/ https://ncbi.nlm.nih.gov/pubmed/24602487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-5-21 |
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