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The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin, a Secoiridoid Glycoside from Swertia chirayita

Swertia chirayita, a medicinal herb inhabiting the challenging terrains and high altitudes of the Himalayas, is a rich source of essential phytochemical isolates. Amarogentin, a bitter secoiridoid glycoside from S. chirayita, shows varied activity in several patho-physiological conditions, predomina...

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Detalhes bibliográficos
Main Authors: Shukla, Shantanu, Bafna, Khushboo, Sundar, Durai, Thorat, Sunil S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946170/
https://ncbi.nlm.nih.gov/pubmed/24603686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090637
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