Amarogentin, a Secoiridoid Glycoside, Abrogates Platelet Activation through PLCγ2-PKC and MAPK Pathways

Amarogentin, an active principle of Gentiana lutea, possess antitumorigenic, antidiabetic, and antioxidative properties. Activation of platelets is associated with intravascular thrombosis and cardiovascular diseases. The present study examined the effects of amarogentin on platelet activation. Amar...

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Detalhes bibliográficos
Main Authors: Yen, Ting-Lin, Lu, Wan-Jung, Lien, Li-Ming, Thomas, Philip Aloysius, Lee, Tzu-Yin, Chiu, Hou-Chang, Sheu, Joen-Rong, Lin, Kuan-Hung
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020542/
https://ncbi.nlm.nih.gov/pubmed/24868545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/728019
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