Role of berberine in anti-bacterial as a high-affinity LPS antagonist binding to TLR4/MD-2 receptor

BACKGROUND: Berberine is an isoquinoline alkaloid mainly extracted from Rhizoma Coptidis and has been shown to possess a potent inhibitory activity against bacterial. However, the role of berberine in anti-bacterial action has not been extensively studied. METHODS: The animal model was established t...

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Bibliografiske detaljer
Main Authors: Chu, Ming, Ding, Ran, Chu, Zheng-yun, Zhang, Ming-bo, Liu, Xiao-yan, Xie, Shao-hua, Zhai, Yan-jun, Wang, Yue-dan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946165/
https://ncbi.nlm.nih.gov/pubmed/24602493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-89
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