Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels

BACKGROUND: Hedgehog signaling plays an important role in embryonic development, organogenesis and cancer. In the adult liver, Hedgehog signaling in non-parenchymal cells has been found to play a role in certain disease states such as fibrosis and cirrhosis. However, whether the Hedgehog pathway is...

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Detalhes bibliográficos
Main Authors: Matz-Soja, Madlen, Aleithe, Susanne, Marbach, Eugenia, Böttger, Jan, Arnold, Katrin, Schmidt-Heck, Wolfgang, Kratzsch, Jürgen, Gebhardt, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946028/
https://ncbi.nlm.nih.gov/pubmed/24548465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-11
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