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Aberrant ceRNA activity drives lung cancer
In a recent issue of Nature, Kumar et al. demonstrate that the oncogenic potential of the Hmga2 gene is largely due to the ability of its transcript to operate as a competing endogenous RNA in a protein coding-independent manner. The Hmga2 mRNA decoys the let-7 microRNA family to regulate Tgfbr3 exp...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945890/ https://ncbi.nlm.nih.gov/pubmed/24525785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.21 |
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