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VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

Lung cancer is one of the most devastating diseases worldwide with high incidence and mortality. Hippo (Hpo) pathway is a conserved regulator of organ size in both Drosophila and mammals. Emerging evidence has suggested the significance of Hpo pathway in cancer development. In this study, we identif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Wenjing, Gao, Yijun, Li, Peixue, Shi, Zhubing, Guo, Tong, Li, Fei, Han, Xiangkun, Feng, Yan, Zheng, Chao, Wang, Zuoyun, Li, Fuming, Chen, Haiquan, Zhou, Zhaocai, Zhang, Lei, Ji, Hongbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945886/
https://ncbi.nlm.nih.gov/pubmed/24458094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.10
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