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Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy.

The relative orientation of helical elements in a folded RNA molecule provides key information about its three-dimensional architecture. We have developed a method that involves extending peripheral helices of an RNA, mounting for electron microscopy in the absence of protein and measuring interheli...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Nakamura, T M, Wang, Y H, Zaug, A J, Griffith, J D, Cech, T R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7588614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00166.x
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