Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy.

The relative orientation of helical elements in a folded RNA molecule provides key information about its three-dimensional architecture. We have developed a method that involves extending peripheral helices of an RNA, mounting for electron microscopy in the absence of protein and measuring interheli...

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Bibliografische Detailangaben

Veröffentlicht in:	EMBO J
Hauptverfasser:	Nakamura, T M, Wang, Y H, Zaug, A J, Griffith, J D, Cech, T R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394583/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7588614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00166.x
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