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Mechanical Boundary Conditions Bias Fibroblast Invasion in a Collagen-Fibrin Wound Model

Because fibroblasts deposit the collagen matrix that determines the mechanical integrity of scar tissue, altering fibroblast invasion could alter wound healing outcomes. Anisotropic mechanical boundary conditions (restraint, stretch, or tension) could affect the rate of fibroblast invasion, but thei...

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Autors principals: Rouillard, Andrew D., Holmes, Jeffrey W.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945786/
https://ncbi.nlm.nih.gov/pubmed/24559996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.002
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