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APOE ε4 worsens hippocampal CA1 apical neuropil atrophy and episodic memory

OBJECTIVES: Using high-resolution structural MRI, we endeavored to study the relationships among APOE ε4, hippocampal subfield and stratal anatomy, and episodic memory. METHODS: Using a cross-sectional design, we studied 11 patients with Alzheimer disease dementia, 14 patients with amnestic mild cog...

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Detalhes bibliográficos
Main Authors: Kerchner, Geoffrey A., Berdnik, Daniela, Shen, Jadon C., Bernstein, Jeffrey D., Fenesy, Michelle C., Deutsch, Gayle K., Wyss-Coray, Tony, Rutt, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945665/
https://ncbi.nlm.nih.gov/pubmed/24453080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000154
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