Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.

To determine which CD3 components are required for early T cell development, we generated mice with a targeted mutation of the CD3-epsilon gene and characterized their T cell populations relative to those found in CD3-zeta/eta-and recombinase activating gene (RAG)-deficient mice. In the absence of i...

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Bibliographic Details
Published in:EMBO J
Main Authors: Malissen, M, Gillet, A, Ardouin, L, Bouvier, G, Trucy, J, Ferrier, P, Vivier, E, Malissen, B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1995
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7588594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00146.x
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