Targeting Extracellular DNA to Deliver IGF-1 to the Injured Heart

There is a great need for the development of therapeutic strategies that can target biomolecules to damaged myocardium. Necrosis of myocardium during a myocardial infarction (MI) is characterized by extracellular release of DNA, which can serve as a potential target for ischemic tissue. Hoechst, a h...

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Detalhes bibliográficos
Main Authors: Khan, Raffay S., Martinez, Mario D., Sy, Jay C., Pendergrass, Karl D., Che, Pao-lin, Brown, Milton E., Cabigas, E. Bernadette, Dasari, Madhuri, Murthy, Niren, Davis, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945489/
https://ncbi.nlm.nih.gov/pubmed/24604065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04257
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