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The delivery of superoxide dismutase encapsulated in polyketal microparticles to rat myocardium and protection from myocardial ischemia-reperfusion injury

Oxidative stress is increased in the myocardium following infarction and plays a significant role in death of cardiac myocytes, leading to cardiac dysfunction. Levels of the endogenous antioxidant Cu/Zn-superoxide dismutase (SOD1) decrease following myocardial infarction. While SOD1 gene therapy stu...

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Bibliografske podrobnosti
Main Authors: Seshadri, Gokulakrishnan, Sy, Jay C., Brown, Milton, Dikalov, Sergey, Yang, Stephen C., Murthy, Niren, Davis, Michael E.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813932/
https://ncbi.nlm.nih.gov/pubmed/19889454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.10.045
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