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Surface functionalization of polyketal microparticles with nitrilotriacetic acid-nickel complexes for efficient protein capture and delivery

Microparticle drug delivery systems have been used for over twenty years to deliver a variety of drugs and therapeutics. However, effective microencapsulation of proteins has been limited by low encapsulation efficiencies, large required amounts of protein, and risk of protein denaturation. In this...

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Detalhes bibliográficos
Main Authors: Sy, Jay C., Phelps, Edward A., García, Andrés J., Murthy, Niren, Davis, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866531/
https://ncbi.nlm.nih.gov/pubmed/20346498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.02.063
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