Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.

The S/G2-specific transcription of the human cdc25C gene is due to the periodic occupation of a repressor element ('cell cycle-dependent element'; CDE) located in the region of the basal promoter. Protein binding to the major groove of the CDE in G0 and G1 results in a phase-specific repre...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Zwicker, J, Lucibello, F C, Wolfraim, L A, Gross, C, Truss, M, Engeland, K, Müller, R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC394543/
https://ncbi.nlm.nih.gov/pubmed/7556094
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