Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.

The S/G2-specific transcription of the human cdc25C gene is due to the periodic occupation of a repressor element ('cell cycle-dependent element'; CDE) located in the region of the basal promoter. Protein binding to the major groove of the CDE in G0 and G1 results in a phase-specific repression of a...

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Detalles Bibliográficos

Publicado en:	EMBO J
Autores principales:	Zwicker, J, Lucibello, F C, Wolfraim, L A, Gross, C, Truss, M, Engeland, K, Müller, R
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00130.x
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