Phosphatidylinositol 3,4,5-trisphosphate is a substrate for the 75 kDa inositol polyphosphate 5-phosphatase and a novel 5-phosphatase which forms a complex with the p85/p110 form of phosphoinositide 3-kinase.

Agonist-stimulated production of phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P3], is considered the primary output signal of activated phosphoinositide (PI) 3-kinase. The physiological targets of this novel phospholipid and the identity of enzymes involved in its metabolism have not yet b...

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Sparad:
Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Jackson, S P, Schoenwaelder, S M, Matzaris, M, Brown, S, Mitchell, C A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556092/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00128.x
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