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The Carboxyl Terminus of FANCE Recruits FANCD2 to the Fanconi Anemia (FA) E3 Ligase Complex to Promote the FA DNA Repair Pathway

Fanconi anemia (FA) is a genome instability syndrome characterized by bone marrow failure and cellular hypersensitivity to DNA cross-linking agents. In response to DNA damage, the FA pathway is activated through the cooperation of 16 FA proteins. A central player in the pathway is a multisubunit E3...

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Autors principals: Polito, David, Cukras, Scott, Wang, Xiaozhe, Spence, Paige, Moreau, Lisa, D'Andrea, Alan D., Kee, Younghoon
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945361/
https://ncbi.nlm.nih.gov/pubmed/24451376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533976
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