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The Mineralocorticoid Receptor Promotes Fibrotic Remodeling in Atrial Fibrillation

We studied the role of the mineralocorticoid receptor (MR) in the signaling that promotes atrial fibrosis. Left atrial myocardium of patients with atrial fibrillation (AF) exhibited 4-fold increased hydroxyproline content compared with patients in sinus rhythm. Expression of MR was similar, as was 1...

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Detalles Bibliográficos
Main Authors: Lavall, Daniel, Selzer, Christian, Schuster, Pia, Lenski, Matthias, Adam, Oliver, Schäfers, Hans-Joachim, Böhm, Michael, Laufs, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945327/
https://ncbi.nlm.nih.gov/pubmed/24469458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.519256
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