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The Mineralocorticoid Receptor Promotes Fibrotic Remodeling in Atrial Fibrillation

We studied the role of the mineralocorticoid receptor (MR) in the signaling that promotes atrial fibrosis. Left atrial myocardium of patients with atrial fibrillation (AF) exhibited 4-fold increased hydroxyproline content compared with patients in sinus rhythm. Expression of MR was similar, as was 1...

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Bibliografische gegevens
Hoofdauteurs: Lavall, Daniel, Selzer, Christian, Schuster, Pia, Lenski, Matthias, Adam, Oliver, Schäfers, Hans-Joachim, Böhm, Michael, Laufs, Ulrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945327/
https://ncbi.nlm.nih.gov/pubmed/24469458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.519256
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