Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Plays a Functional Role in Osteoclast Differentiation and Bone Resorption Activity

Lysophosphatidic acid (LPA) is a natural bioactive lipid that acts through six different G protein-coupled receptors (LPA(1–6)) with pleiotropic activities on multiple cell types. We have previously demonstrated that LPA is necessary for successful in vitro osteoclastogenesis of bone marrow cells. B...

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Autori principali: David, Marion, Machuca-Gayet, Irma, Kikuta, Junichi, Ottewell, Penelope, Mima, Fuka, Leblanc, Raphael, Bonnelye, Edith, Ribeiro, Johnny, Holen, Ingunn, Vales, Rùben Lopez, Jurdic, Pierre, Chun, Jerold, Clézardin, Philippe, Ishii, Masaru, Peyruchaud, Olivier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945319/
https://ncbi.nlm.nih.gov/pubmed/24429286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533232
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